Hormones are chemical messengers produced in cells within our bodies. They send out specific signals to the organs and cells to start, stop or regulate a function, they are transported to the action area within the blood stream and control all areas of healthy function and development of the body.
There are approximately 70 known hormones, each in control of important body functions. The science of hormones "Endocrinology" is relatively new - the hormone insulin and it's effects was only discovered approximately 80 years ago, saving millions of lives and as research continues new discoveries are unfolding.
With regards to appetite and hunger there are 2 main hormones. These hormones send signals to the brain, specifically to the area known as the hypothalamus. The hypothalamus controls appetite by coordinating the functions of the metabolism, liver, intestines and fat storing cells, it reacts to the signals from the appetite hormones.
Appetite Stimulant
Ghrelin
Ghrelin is a fast acting hormone that stimulates appetite, food intake and increases the storage of calories in the fat cells in our bodies. It is referred to as "The Hunger Hormone". It signals to your brain that you need to eat and stimulates the reward centre of your brain, making you crave your most rewarding foods, the higher the levels increase, the stronger your cravings get.
Ghrelin promotes physical feelings of hunger and if you have a regular pattern to meals, the levels of ghrelin rise around the time you usually have your meals and higher still when you are drastically reducing your calorie intake or fasting.
Frequent eating and overeating affects ghrelin production by keeping levels low. This may sound good, as hunger pangs are kept at bay, but this eating behaviour is not healthy and leads to being overweight and obese, which is not good for your general physical and mental health. A recent study by Professor Colin Chapman of The University of Sweden, showed that overweight and obese people in their Study Group had decreased levels of ghrelin in their blood stream. This was probably due to the frequent eating behaviour. When successful weight loss was achieved, the ghrelin levels raised to normal levels again. It is important to understand that overeating leads to Ghrelin Resistance and subsequent weight gain and obesity - this may have serious consequences for your general health and wellbeing.
Frequent eating and overeating affects ghrelin production by keeping levels low. This may sound good, as hunger pangs are kept at bay, but this eating behaviour is not healthy and leads to being overweight and obese, which is not good for your general physical and mental health. A recent study by Professor Colin Chapman of The University of Sweden, showed that overweight and obese people in their Study Group had decreased levels of ghrelin in their blood stream. This was probably due to the frequent eating behaviour. When successful weight loss was achieved, the ghrelin levels raised to normal levels again. It is important to understand that overeating leads to Ghrelin Resistance and subsequent weight gain and obesity - this may have serious consequences for your general health and wellbeing.
The Appetite Suppressant
Leptin
The hormone Leptin is an appetite suppressant (stops you eating) and is produced in the fat storing cells of your body. When you eat, leptin levels rise and travel through the blood stream to the brain and signal that you are full, to stop eating and increase the rate of metabolism (speed at which you burn calories) This hormonal action regulates your body weight.
The more overweight you are, the more leptin is produced. Significant studies have shown that the overweight and obese have high levels of leptin in the blood stream ( due to larger fat stores) The constant high levels of leptin causes a disruption to the uptake by the brain, Leptin Resistance. The brain does not respond to the signal to stop eating, it doesn't receive the message that enough calories have been eaten and that the fat stores are full and so it continues to put out demands that the body should eat more as it is starving.
Clinical studies have shown that rats injected with high levels of leptin soon developed Leptin Resistance and didn't react to leptin's appetite lowering effects. They ate more and gained more weight, which in turn produced more leptin - a vicious cycle.
Other clinical studies have shown that successful weight loss causes leptin levels to decrease and return to normal levels and eating 2 -3 meals a day with no snacking will allow those levels to fluctuate normally and for the " stop eating" signals to be received by the brain.
Overeating and obesity leads to resistance of both of the appetite hormones, which in turn leads to more weight gain. The good news is that with continued healthy eating you can prevent this from occurring and if you are already overweight you can reverse the resistance by weight loss through a healthy eating plan and some exercise.
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